Atopic dermatitis
Nova has built a mechanistic model of AD representing the interplay between the skin barrier and the immune system in a pediatric population.
Atopic dermatitis case study
Atopic dermatitis (AD) is characterized by a complex pathophysiology with a wide spectrum of phenotypes. This high diversity makes mechanistic in silico approaches particularly adapted for guiding clinical development.
In the context of the bacterial lysate OM-85’s development to treat atopic dermatitis, [1] OM Pharma wanted to conduct an in silico exploration of the immune mechanisms driving the treatment response in order to characterize the best responders.
Nova has built a mechanistic model of AD representing the interplay between the skin barrier and the immune system in a pediatric population.
Summary
- The challenge
- The solution
- The outcome
- The references
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