Evidence
Case studies & deep dives
Real-world applications of Jinkō across disease areas: how mechanistic modeling shaped trial decisions before the first patient enrolled.
Atopic dermatitis
Nova has built a mechanistic model of AD representing the interplay between the skin barrier and the immune system in a pediatric population.
NASH
Non-alcoholic fatty liver disease (NAFLD) is a common disorder characterized by an accumulation of excess fat inthe liver (hepatic steatosis).
Respiratory tract infection
Even before the Covid-19 pandemic, RTIs were a leading cause of hospitalization in children, many of whom may go on to develop chronic conditions such as asthma.
Myocardial reperfusion injury
Applied to myocardial reperfusion injury this in silico clinical trial shows the efficacy of the inhibition of reactive oxygen species production in ST elevated myocardial infarction.
LUAD Non-Small Cell Lung Cancer (NSCLC)
Non small cell lung cancer (NSCLC) makes up the majority of lung cancer cases and there is significant unmet medical need in this indication.
Hepatitis B
Exploring a drug candidate, the nova team simulated a Phase 2 trial, exploring a number of treatment regimens on a large variety of patients and treatment combinations.