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Nova In Silico will be at ACoP 2026Meet the team and see our programDetails here

Model library

Disease and treatment models across major therapeutic areas, ready to simulate

Nova builds mechanistic QSP models in-house, and every Jinkō subscription includes a library of disease and treatment models imported from the literature to give you a head start.

18 Nova-built models · 102 literature models · 72 with a peer-reviewed source

Flagship models

Our most rigorously tested, published in-house models.

OncologyPeer-reviewed

NSCLC: EGFR-mutated

EGFR signaling, tumor growth, and acquired resistance

Prospective PFS prediction of the Phase III MARIPOSA trial matched the readout.

Peer-reviewed, npj Systems Biology and Applications, 2023
OncologyPublished

T-cell engager (TCE) platform

From bispecific binding to T-cell mediated tumor kill

Translational dose selection for T-cell-engaging bispecific antibodies.

Poster, ACOP 2023
OncologyPublished

Antibody-drug conjugate (ADC) platform

Antibody targeting, payload release, and tumor response

Payload delivery and tumor response modeling for ADC design.

Poster, ACOP 2024
CardiometabolicPeer-reviewed

Atherosclerotic cardiovascular disease (ASCVD)

From LDL-C and lipids to plaque and cardiovascular events

Prospective LDL-C prediction of the Phase III CORALreef trial matched the readout.

Peer-reviewed, npj Digital Medicine, 2025
Immunology & inflammationPeer-reviewed

Atopic dermatitis

Skin barrier breakdown and the immune cascade

Skin barrier and immune pathway biomarkers for trial design and stratification.

Peer-reviewed, Journal of Allergy and Clinical Immunology, 2024
Infectious diseasePublished

Influenza

Viral kinetics, immunization, and vaccine efficacy

Multi-strain vaccine efficacy across populations and age groups.

Poster, ASCPT 2023

Every model is accessed inside Jinkō. Here is how the two kinds differ.

Nova-built

Nova-built models

Mechanistic QSP models our scientists build in-house, including our published, peer-reviewed flagship models. Built for your program, and available in Jinkō.

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Imported from literature

Literature library

More than 100 disease and treatment models structured from published research, included with every Jinkō subscription. A fast starting point for building and simulating, with lighter curation than our in-house work.

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Library explorer

Search 120 models across every therapeutic area

Filter by disease, target, model type, and evidence, then open any model in Jinkō.

Catalog updated 2026-08-18

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Showing 25 of 119 models

Sort:
ModelAreaSourceEvidence
Nonalcoholic steatohepatitis (NASH)
Nonalcoholic steatohepatitis (NASH), mechanistic model available on demand
Hepatology
Nova-built
Non Small Cell Lung Cancer
EGFR-mutated non-small cell lung carcinoma, mechanistic model available on demand
Oncology
Nova-built
Atopic Dermatitis
FLG-mutated atopic eczema, mechanistic model available on demand
Immunology & inflammation
Nova-built
Hepatitis B Virus (HBV)HBeAg-positiveHBeAg-negative
Hepatitis B virus infection, HBeAg-negative and HBeAg-positive, mechanistic model available on demand
Infectious disease
Nova-built
Influenza Vaccine
Influenza, mechanistic model available on demand
Infectious disease
Nova-built
Atherosclerotic Cardiovascular Disease (ASCVD)
Atherosclerotic cardiovascular disease, mechanistic model available on demand
Cardiometabolic
Nova-built
Acute Myeloid Leukemia (AML)
Acute myeloid leukemia, mechanistic model available on demand
Oncology
Nova-built
Prostate Cancer
Prostate Cancer, mechanistic model available on demand
Oncology
Nova-built
Nova - Gefitinib
Nova - Gefitinib - available on demand
Oncology
Nova-built
Antibody-drug conjugate (ADC) platform
Antibody-drug conjugate (ADC) platform, mechanistic model available on demand
Oncology
Nova-built
T-cell engager (TCE) platform
T-cell engager (TCE) platform, mechanistic model available on demand
Oncology
Nova-built
Nova - Cisplatin
Nova - Cisplatin - available on demand
Oncology
Nova-built
Nova - Osimertinib
Nova - Osimertinib - available on demand
Oncology
Nova-built
Nova - Entecavir
Nova - Entecavir - available on demand
Infectious disease
Nova-built
Nova - PegIfn2a
Nova - PegIfn2a - available on demand
Oncology
Nova-built
Nova - Venetoclax
Nova - Venetoclax - available on demand
Oncology
Nova-built
Nova - Ezetimibe
Nova - Ezetimibe - available on demand
Cardiometabolic
Nova-built
Hepatic glucose metabolism
Reusable building block: Hepatic glucose metabolism
Hepatology
Literature
Bone Health and Mineral Model
Reusable building block: Bone Health and Mineral Model
Oncology
Literature
Cell Cycle regulation in response to DNA damage
Reusable building block: Cell Cycle regulation in response to DNA damage
Oncology
Literature
Pancreas model
Reusable building block: Pancreas model
Cardiometabolic
Literature
Triple negative breast cancer
Disease and treatment model of triple-negative breast carcinoma
Oncology
Literature
NSCLC
Disease and treatment model of non-small cell lung carcinoma
Oncology
Literature
Triple Negative Breast Cancer - With Metastasis
Mechanistic QSP model of triple-negative breast carcinoma
Oncology
Literature
Bile Acid Distribution and Metabolism
Reusable building block: Bile Acid Distribution and Metabolism
Hepatology
Literature
Browse the full library in Jinkō

Two ways in, one platform.

Start simulating today. Get 102 literature models included with Jinkō.

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Do not see your therapeutic area?

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